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small town southern charm meets big city excitement...welcome to the Hampton Inn Florence-Midtown.Located on the banks of the beautiful Tennessee River, Florence, Alabama, is rich with Native American and Civil War history. This picturesque area in the Northwest corner of Alabama offers a delightful blend of small-town Southern hospitality with the amenities of a large city. Discover it all when you stay at the Hampton Inn� Florence-Midtown hotel.Whether you're here on business or vacation, you'll want a Florence hotel that offers all the comforts of home. Look no further than the Hampton Inn Florence-Midtown hotel. We're conveniently located on Highway 72 just one mile from the Regency Square Mall. Our Florence hotel offers the perfect home base from which to explore all our vibrant city has to offer, including: great restaurants, shopping malls, golf courses, memorials and museums. You'll find it all just moments from our hotel in Florence.services & amenitiesEven if you're in Florence to enjoy the great outdoors, we want you to enjoy our great indoors as well. That's why we offer a full range of services and amenities at our hotel to make your stay with us exceptional.Are you planning a meeting? Wedding? Family reunion? Little League game? Let us help you with our easy booking and rooming list management tools.* Meetings & Events * Local Restaurant Guide